Chip Based Unilamellar Vesicle Formation and Dispensing Using Dielectrophoresis
نویسندگان
چکیده
Vesicles, also known as liposome, are bilayers of lipid molecules enclosing a fluidic media. Vesicles can be formed by spontaneous assembling of phospholipid bilayer separating two different solvent media. Alternatively, vesicles can be formed as solid supported membranes. Such vesicles have potential in understanding the structural and other properties of cellular membranes and utility in targeted drug delivery systems and bio-sensors. In this paper, we have demonstrated an L-DEP based on-chip, vesicle dispensing scheme capable of dispensing a population of identically sized, large unilamellar vesicles and furthermore deposition of lipid bilayer onto polystyrene microbeads in order to produce biofunctional membranes.
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